expert reviews
Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment
Review of: C.A., Siegel M.A., Elting L.S. Lancet Oncol 2006;7(6): 508–514.Although bisphosphonates have been used clinically for more than 30 years, complete knowledge of their pharmacokinetics and pharmacodynamics has not yet...
Cancer immunotherapy: moving beyond current vaccines
The future looks bright if the following criteria can be met: (1) in vivo generation of sufficient numbers of immune cells to recognize tumor antigens (2) successful trafficking of these cells to infiltrate the tumor stroma, and...
Adjuvant cisplatin plus methotrexate versus methotrexate, vinblastine, epirubicine and cisplatin in locally advanced bladder cancer: results of a randomized, multicenter phase III trial (AUO-AB 05/95).
Review of: J. Lehmann, M. Retz, C.Wiemers, J. Beck, J. Th¸roff et al. J Clin Oncol, 23, 22, 4963-4972, 2005.
This paper reports the results of a large multicenter trial conducted by the German Urological Oncology Group...
Effects of Long-term Vitamin E Supplementation on Cardiovascular Events and CancerA Randomized Controlled Trial
The major finding of the HOPE and HOPETOO trials, is the lack of benefit for vitamin E in preventing cancer or major cardiovascular events after a prolonged period of treatment and observation








