key articles
Effects of fluorescent light-guided transurethral resection on non-muscle-invasive bladder cancer
Friday, 3 February 2012- It was well known that FL-guided TURBT could reduce the residual rate of NMIBC, but a systematic review conducted by P. Shen and colleagues suggested that it was not superior to conventional WL-guided...
Edited by: JV
Clinical nodal staging scores for bladder cancer
Monday, 30 January 2012- Radical cystectomy (RC) with pelvic lymph node dissection (LND) is the standard of care for refractory non-muscle-invasive and muscle-invasive bladder cancer. Although consensus exists on the need for...
Edited by: JV
A novel role of Id-1 in regulating epithelial-to-mesenchymal transition in bladder cancer
Wednesday, 11 January 2012- Inhibitor of differentiation or DNA binding -1 (Id-1) has been shown to be increased in several types of advanced cancer, and to be associated with aggressive and metastatic abilities of cancer cells....
Edited by: JV
Efficacy of perioperative gemcitabine and cisplatin vs MVAC in locally advanced bladder cancer
Thursday, 5 January 2012- O. Yeshchina and colleagues conducted a study to compare the outcomes of patients treated in the perioperative setting with methotrexate, vinblastine, adriamycin, and cisplatin (MVAC) versus gemcitabine...
Edited by: JV
High expression of polo-like kinase 1 linked with bladder cancer recurrence and metastasis
Friday, 30 December 2011- Polo-like kinase 1 (Plk1) has been widely pursued as an oncology target because it is overexpressed in several human tumor types. To investigate whether Plk1 plays a general role in...
Edited by: JV
Randomised phase 2-3 trial: assessing gemcitabine/carboplatin and M-CAVI in advanced urothelial cancer patients
Thursday, 15 December 2011- M. De Santis and colleagues conducted the first randomised phase II/III trial comparing two carboplatin-based chemotherapy regimens in patients with urothelial cancer who are ineligible (“unfit”) for...
Edited by: JV
Upper urinary tract recurrence after radical cystectomy for BCa: incidence and risk factors
Monday, 5 December 2011- A group of Japanese researchers conducted a study to examine the incidence of and the risk factors for upper urinary tract recurrence in patients undergoing a radical cystectomy for bladder cancer, and to...
Edited by: JV
Salvage surgery after chemo: does it have clinical impact on survival of metastatic urothelial carcinoma patients?
Wednesday, 23 November 2011- The clinical impact of salvage surgery after chemotherapy on cancer survival of patients with metastatic urothelial carcinoma is controversial.
K. Bekku and colleagues conducted a study to verify...
Edited by: JV
Value of bladder mapping and prostatic urethra biopsies in detecting carcinoma in situ
Thursday, 10 November 2011- It is well known that CIS is a major risk factor for muscle-invasive bladder cancer and that this entity can be difficult to diagnose. Taking cold-cup mapping biopsies from different areas of the...
Edited by: JV
