expert reviews
Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment
Review of: C.A., Siegel M.A., Elting L.S. Lancet Oncol 2006;7(6): 508–514.Although bisphosphonates have been used clinically for more than 30 years, complete knowledge of their pharmacokinetics and pharmacodynamics has not yet...
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans- Tasman Radiation Oncology Group 96.01 randomised controlled trial
Review of: Denham J.W, Steigler A., Lamb D.S., Joseph D., Mameghan H., Turner S., Matthews J., Franklin I., Atkinson C., North J., Poulsen M., Christie D., Spry N.A., Tai K.H., Wynne C., Duchesne G., Kovacev O., D’Este C. Lancet...
Pomegranate Fruit Juice for Chemoprevention and Chemotherapy of Prostate Cancer
Review of: Malik A., Afaq F., Sarfaraz S., Adhami V.M., Syed D.N. and Mukhtar H. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14813-14818.What’s new in chemoprevention of prostate cancer using natural dietary...
Lymphovascular invasion in prostate cancer - prognostic significance in patients treated with radiotherapy after radical prostatectomy
Review of: Brooks JP, Albert PS, O’Connell J, McLeod DG, Poggi MM. Cancer 2006;106(7):1521-1526.Lymphovascular invasion (LVI) is found on standard hematoxylin and eosin staining and defined as the unequivocal presence of tumour...
Delayed surgery in well-selected prostate cancer patients not associated with worse outcome
The authors conclude that delayed prostate cancer surgery for patients with small, lower-grade prostate cancers does not appear to compromise curability and they point to two important outcomes from the present study
Identification of a novel gammaretrovirus in prostate tumors of patients Homozygous for R462Q RNASEL Variant
the results presented by this collaborative group may be of utmost interest since it seems like xenotropic LuLV-related viruses can produce an authentic human infection, and strongly implicate RNase L activity in the prevention...
Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk
Although this study indicates a role of vitamin E supplementation in male smokers and ß-carotene supplementation in men with low dietary ß-carotene intakes
Salvage radical prostatectomy for radiorecurrent prostate cancer: Indications and results
Review of: Darras J, Joniau S, Van Poppel H. Eur J Surg Oncol. 2006 Jun 29; [Epub ahead of print]Salvage radical prostatectomy has previously been considered to be a major challenge even for welltrained surgeons. However, it may...
Risk factors for prostate cancer: A national case-control study
In the last decade, a multitude of different risk factors for development of prostate cancer has been studied extensively, including obesity, height, weight, body mass index, physical activity, dietary factors, in particular...
Dose-response in radiotherapy for localized prostate cancer: Results of the Dutch Multicenter Randomized Phase III Trial comparing 68 Gy of radiotherapy with 78 Gy
This is the largest randomized multicentre trial so far that shows a significant improvement in freedom of failure in prostate cancer patients treated with a higher dose of radiotherapy



