expert reviews
Detection of occult lymph node metastasis in locally advanced nodenegative prostate cancer
The results of this study are clinically not surprising. The true incidence of occult metastatic disease in clinically localised prostate cancer may never be determined as probably even more refined methods of detection would...
Celecoxib versus placebo for men with prostate cancer and a rising serum PSA after radical prostatectomy and/or radiation therapy
So what is the clinical benefit, if any? The use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been linked with a decreased risk for several malignancies
Phase II Study of Pomegranate Juice for men with rising PSA following surgery or radiation for prostate cancer
This study adds further data to the growing body of evidence on the effects various nutrients may or may not have on prostate cancer
Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy
The interesting question whether converse patients with localized prostate cancer and without significant increases in PSA can safely be followed without treatment cannot be answered at present
Cancer immunotherapy: moving beyond current vaccines
The future looks bright if the following criteria can be met: (1) in vivo generation of sufficient numbers of immune cells to recognize tumor antigens (2) successful trafficking of these cells to infiltrate the tumor stroma, and...
Natural History of Early, Localized Prostate Cancer
The mean follow-up time in this study was only 6.2 years and it will take several more years of follow-up to better assess whether the overall mortality will be affected by early treatment with radical prostatectomy
Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911)
The histopathological grading was based on the WHO system and not on the Gleason system. Most patients were not treated with conformal threedimensional radiotherapy and the methods used today are also based on improved imaging...
Increased risk of rectal cancer after prostate radiation: a population-based study
The risk of developing rectal cancer after external beam radiation for prostate cancer is moderately increased and in the same magnitude as having a first-degree relative with colorectal cancer
Autoantibody Signatures in Prostate Cancer
Wang et al. report work that takes advantage of antitumour immunity and propose a method for the detection of prostate cancer on the basis of the patient’s ‘autoantibody signatures’, similar to autoantibodies against multiple...
Robotic-assisted laparoscopic prostatectomy: what is the learning curve?
Many surgeons have suggested that the robotassisted technique has a shorter learning curve than the conventional laparoscopic technique, i.e. is easier to learn for the surgeon highly experienced in the open retropubic technique...















