expert reviews
Safely reducing length of stay after open radical retropubic prostatectomy under the guidance of a clinical care pathway
This study provides an interesting insight into the US-American hospital system. Compared to the European situation, the cost-driven reduction in hospital-stay has been carried a lot further in the American system
Neuroanatomy of the normal prostate
The authors of this study have taken the frequency of perineural invasion in prostatic cancer as a starting point to further investigate prostatic neuroanatomy in a quantitative manner
Increased risk of rectal cancer after prostate radiation: a population-based study
These two studies based on large data analyses represent important and significant findings in view of long-term adverse treatment effects of radiotherapy
Risk of fracture after androgen deprivation for prostate cancer
It is still an open question how to best handle this group of patients. Current recommendations are that men with prostate cancer who are being treated with androgen deprivation should have their bone mineral density monitored...
Cannabinoid receptor as a novel target for the treatment of prostate cancer
In this recent paper, Sarfaraz and collaborators show for the first time that expression levels of both cannabinoid receptors CB1, CB2, are higher in human prostate cancer cells than in normal cells
20-year outcomes following conservative management of clinical localized prostate cancer.
The clinical implications of both studies should be the same; that men with well differentiated tumours do not always benefit from aggressive treatment
Sca-1 expression identified stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue
Burger and colleagues have previously shown a high density of prostatic stem cells in the proximal regions of the prostatic ducts
Effects of Long-term Vitamin E Supplementation on Cardiovascular Events and CancerA Randomized Controlled Trial
The major finding of the HOPE and HOPETOO trials, is the lack of benefit for vitamin E in preventing cancer or major cardiovascular events after a prolonged period of treatment and observation
mtDNA mutations increase tumorigenicity in prostate cancer
As the authors were able to validate both their assumptions on prostate cancer, they drew the conclusion that mtDNA mutations do play an important role in the etiology of prostate cancer















