key articles
Characterisation of PCa lesions in heterozygous Men1 mutant mice
Thursday, 29 July 2010- Mutations of the MEN1 gene predispose to multiple endocrine neoplasia type 1 (MEN1) syndrome. Our group and others have shown that Men1 disruption in mice recapitulates MEN1 pathology. Intriguingly, rare...
Edited by: JV
Second to fourth digit ratio: a predictor of PSA level and PCa
Thursday, 29 July 2010- A group of Korean researchers conducted a study to investigate the relationships between the 2nd to 4th digit ratio (digit ratio) and prostate volume, prostate-specific antigen (PSA) level, and the...
Edited by: JV
Short rare hTERT-VNTR 2-2nd alleles linked with PCa susceptibility
Wednesday, 28 July 2010- The hTERT (human telomerase reverse transcriptase) gene contains five variable number tandem repeats (VNTR) and previous studies have described polymorphisms for hTERT-VNTR2-2nd.
Se-Lyun Yoon and...
Edited by: JV
Outcome of patients with localised PCa treated by radiotherapy
Tuesday, 27 July 2010- N. Suzuki and colleagues conducted a study on the outcome of patients with localised prostate cancer who underwent radiotherapy after confirming the absence of lymph node invasion. They published their...
Edited by: JV
HIF1alfa isoforms in benign and malignant prostate tissue
Friday, 23 July 2010- Neuroendocrine (NE) differentiation in prostate cancer has been correlated with a poor prognosis and hormone refractory disease.
In a previous report, M. Nastaran and colleagues demonstrated the presence...
Edited by: JV
Prostate cancer risk variant found to be in a functional DNA sequence linked with disease
Thursday, 15 July 2010- Recent genetic association studies have uncovered a number of DNA variants associated with prostate cancer. However, some of these risk variants lie outside of genes, posing a challenge to researchers...
Edited by: JV
Robotic surgery and demographics in patients choosing to undergo radical prostatectomy
Wednesday, 14 July 2010- A group of researchers reported on the differences in patient demographics in those men choosing to undergo radical prostatectomy in a UK centre where there is no influence of robotic surgery and in those...
Edited by: JV
Genetic translocations and the risk for more aggressive forms of prostate cancer
Thursday, 8 July 2010- A research group at Memorial Sloan-Kettering Cancer Center has published data indicating that translocation and/or deletion of the TMPRSS2-ERG fusion gene — which occurs in about 50% of the...
Edited by: ES
Screening cost-effective after prostate cancer
Thursday, 8 July 2010- Bone-density screening can be cost effective after prostate cancer treatment, a new study has found.
According to background information cited in the study, androgen deprivation therapy (ADT), which is...
Edited by: ES
