key articles
Serum vitamin D concentration and prostate cancer risk: a nested case-control study
Wednesday, 2 July 2008 - Epidemiological studies have yielded inconsistent associations between vitamin D status and prostate cancer risk, and few studies have evaluated whether the associations vary by disease aggressiveness....
Authors: Ahn et al.
Eat more beans, less prostate cancer risk
Wednesday, 2 July 2008 - Association of legume, soy and isoflavone intake with prostate cancer risk is yet inconclusive, although soy has received considerable attention due to its high phytoestrogen content. Therefore, Park et...
Authors: Park et al.
Maintenance of intratumoral androgens in metastatic prostate cancer
Sunday, 29 June 2008 - Therapy for advanced prostate cancer focuses on suppressing systemic androgens and blocking activation of the androgen receptor (AR). Despite anorchid serum androgen levels, nearly all patients develop...
Authors: Montgomery et al.
Docetaxel administered every 3 weeks with prednisone for metastatic hormone-refractory prostate cancer patients
Saturday, 28 June 2008 - Saad et al. (2008) studied the use of docetaxel 75 mg/m2 intravenously every 3 weeks plus prednisone 5 mg orally twice daily in men with metastatic hormone-refractory prostate cancer (HRPC) progressing...
Authors: Saad et al.
Supportive care needs of men living with prostate cancer in England
Saturday, 28 June 2008 - Men with prostate cancer have various treatment options depending upon their stage of disease, age and presence of comorbidity. However, these treatments typically induce side effects, which generate...
Authors: Ream et al.
Effect of biopsy-core numbers on the concordance between prostate biopsy and prostatectomy Gleason score
Friday, 27 June 2008 - Studies analyzing the concordance of biopsy and radical prostatectomy (RP) Gleason scores have limitations. Some included two or more centers, used historical controls from the early prostate specific...
Authors: Antunes et al.
Diagnostic radiation procedures and risk of prostate cancer
Friday, 27 June 2008 - Exposure to ionising radiation is an established risk factor for many cancers. In a case-control study, Myles et al. (2008) investigated whether exposure to low dose ionisation radiation from diagnostic...
Authors: Myles et al.
Risks and benefits of bisphosphonates
Friday, 27 June 2008 - Bone is the most common site for metastasis in cancer and is of particular clinical importance in breast and prostate cancers due to the prevalence of these diseases. Bone metastases result in considerable...
Authors: Coleman et al.
Estimating rates of true high-grade disease in the Prostate Cancer Prevention Trial
Friday, 27 June 2008 - The Prostate Cancer Prevention Trial (PCPT) showed a decreased prostate cancer rate but an increased rate of high Gleason grade disease on biopsy for finasteride versus placebo. The results from radical...
Authors: Pinsky et al.
Pathologic characteristics of cancers detected in the Prostate Cancer Prevention Trial
Thursday, 26 June 2008 - The Prostate Cancer Prevention Trial (PCPT) showed a risk of prostate cancer at prostate-specific antigen (PSA) < 4.0 ng/mL and that prostate cancer risk is reduced by finasteride. A major concern about...
Authors: Lucia et al.
