key articles
Identification of candidate prostate cancer genes through comparative expression-profiling of seminal vesicle
Thursday, 26 June 2008 - Prostate cancer is the most frequently diagnosed cancer among men in the United States. In contrast, cancer of the seminal vesicle is exceedingly rare, despite that the prostate and seminal vesicle share...
Authors: Thompson et al.
Detailed analysis of histopathological parameters in radical prostatectomy specimens and PCA3 urine test results
Thursday, 26 June 2008 - Due to the drawbacks of serum prostate-specific antigen, there is an ongoing search for new diagnostic and prognostic prostate cancer (PCa) markers. Prostate Cancer Gene 3 (PCA3) has proven to be of value...
Authors: van Gils et al.
Finasteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modelling approach
Thursday, 26 June 2008 - Finasteride taken for 7 years in the Prostate Cancer Prevention Trial (PCPT) reduced the risk of prostate cancer by 25%, but with an apparent increased risk of high-grade disease. Subsequent analyses...
Authors: Redman et al.
Novel small molecule inhibitors for prostate-specific antigen
Wednesday, 25 June 2008 - Prostate-specific antigen (PSA or KLK3) has been shown to inhibit angiogenesis, but it might also have tumor promoting activities. Thus, it may be possible to modulate prostate cancer growth by...
Authors: Koistinen et al.
Update of Dutch multicenter dose-escalation trial of radiotherapy for localized prostate cancer
Wednesday, 25 June 2008 - Al-Mamgani et al. (2008) updated the analysis of the Dutch dose-escalation trial of radiotherapy for prostate cancer.
A total of 669 patients with localized prostate cancer were randomly assigned to...
Authors: Al-Mamgani et al.
Image-guided radiotherapy and toxicity profile in whole pelvic-treated high-risk prostate cancer
Tuesday, 24 June 2008 - Chung et al. (2008) evaluated the impact of adding image-guided (IG) technique to intensity-modulated radiotherapy (IMRT) on dosimetric avoidance of organs at risk (OAR) and acute toxicities.
A total of...
Authors: Chung et al.
Newer imaging modalities for target localization in radiation of prostate cancer and lymph node metastases
Tuesday, 24 June 2008 - Precise localization of prostate cancer and the drainage lymph nodes is mandatory to define an accurate clinical target volume for conformal radiotherapy. Better target definition and delineation on a...
Authors: John et al.
Quality of life in men treated with carbon ion therapy for prostate cancer
Tuesday, 24 June 2008 - Wakatsuki et al. (2008) prospectively assessed patient quality of life (QOL) after carbon ion radiotherapy (C-ion RT) for prostate cancer, using established questionnaires.
The subjects were 150 patients...
Authors: Wakatsuki et al.
Predicting biochemical failure and overall survival with prostate specific antigen changes
Tuesday, 24 June 2008 - Soto et al. (2008) determined whether intratherapy prostate-specific antigen (itPSA) changes during radiotherapy (RT) predict prostate cancer outcomes.
The authors retrospectively identified patients...
Authors: Soto et al.
Assessing pathological prostate cancer characteristics in men with favorable biopsy features
Monday, 23 June 2008 - The rate of insignificant prostate cancer (IPCa) is increasing. Chun et al. (2008) examined three end points in patients with a single, positive core and no high-grade prostate cancer (PCa) at biopsy,...
Authors: Chun et al.
