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Genes may explain high rate of kidney disease in African Americans

Wednesday, 21 July 2010- Two variants in a single gene may account for many cases of kidney disease in African Americans, but may also have helped their ancestors -- as well as those living in regions of present-day Africa --...

Edited by: JV

Strong link between gene expression and recurrence risk in localised RCC

Tuesday, 8 June 2010- A joint study on early-stage renal cell carcinoma (RCC) prognosis demonstrated a strong correlation between gene expression and recurrence risk in patients with localised RCC. The study, jointly conducted by...

Edited by: JV

Similarities found between Wilms tumor cells and normal kidney stem cells

Tuesday, 8 June 2010- A detailed analysis of the epigenetics – factors controlling when and in what tissues genes are expressed – of Wilms tumour reveals striking similarities to stem cells normally found in foetal kidneys. These...

Edited by: ES

Ablation is effective as traditional surgery in treating kidney cancer

Friday, 4 June 2010- A minimally invasive technique used to destroy kidney tumours with an electrically controlled heating probe showed similar effectiveness as surgical removal of tumours in curbing cancer recurrence rates for...

Edited by: JV

Mayo Clinic study identifies surgical means to boost kidney cancer survival

Friday, 4 June 2010- When kidney cancer spreads to other body parts, patients usually receive a poor prognosis. A new Mayo Clinic study examined the benefits of surgical treatment of kidney cancer, specifically renal cell...

Edited by: JV

Temsirolimus and bevacizumab combi in metastatic RCC: TORAVA trial

Wednesday, 2 June 2010- Temsirolimus (T) and bevacizumab (B) have been approved for the treatment of metastatic renal cell carcinoma (mRCC). The T-B combination has proven feasible at full doses of each agent with promising...

Edited by: JV

Researchers find papillary renal cell carcinoma unresponsive to sunitinib

Tuesday, 1 June 2010- Of the more than 38,000 Americans diagnosed with renal cell carcinoma (RCC) each year, approximately 20% have non-clear cell forms of the disease. New findings shows that a non-clear cell form of kidney...

Edited by: ES

Predictive factors for ipsilateral recurrence after nephron-sparing surgery

Tuesday, 25 May 2010- Ipsilateral recurrence after nephron-sparing surgery (NSS) is rare, and little is known about its specific determinants. J. C. Bernhard  and colleagues conducted a study to determine clinical or...

Edited by: JV

Researchers find genetic secrets to clear cell renal cell carcinoma

Friday, 21 May 2010- By examining expression of every human gene in clear cell renal cell carcinoma (ccRCC) compared to normal kidney cells, researchers at Mayo Clinic's campus in Florida, USA, have discovered gene signatures...

Edited by: JV

Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in RCC

Thursday, 13 May 2010- Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and cancer etiogenesis and development.

A.Varona...

Adhesion of kidney cancer cells to endothelial cells depends on PKCmu

Monday, 10 May 2010- The formation of metastases includes the separation of tumour cells from the primary tumour, cell migration into subendothelial tissue and cell proliferation in secondary organ. In this process, cell adhesion...

Edited by: JV

Researchers found no link between drinking milk and kidney cancer risk

Monday, 10 May 2010- A study has cast doubt on previous research that suggested drinking milk was related to factors that may increase the risk of renal cell cancer.

"The data in this study provide no concrete evidence of a...

Edited by: JV

Treatment saves kidneys with large cancerous tumours

Thursday, 6 May 2010- A multicenter team of investigators led by the University of California, San Diego School of Medicine has demonstrated, for the first time, the safety and efficacy of a targeted medication to shrink advanced...

Edited by ES

Identifying progression risk after surgery for localised kidney cancer

Tuesday, 4 May 2010- A group of US researchers conducted a study to identify factors in a large cohort of patients with pathologically localised renal cell carcinoma (RCC) that predicted disease progression after surgery, as RCC...

Edited by: JV

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