key articles
Brain metastasis from renal cell carcinoma: presence, recurrence, and survival
Thursday, 21 August 2008 - Patients with renal cell carcinoma brain metastases (RCCBM) are frequently excluded from trials and no guidelines currently exist regarding central nervous system (CNS) surveillance or treatment. Shuch...
Authors: Shuch et al.
Efficacy of everolimus in advanced renal cell carcinoma
Monday, 18 August 2008 - Everolimus (RAD001) is an orally administered inhibitor of the mammalian target of rapamycin (mTOR), a therapeutic target for metastatic renal cell carcinoma. Motzer et al. (2008) did a phase III,...
Authors: Motzer et al.
Performance status and cytoreductive nephrectomy : Redefining management in patients with poor performance
Friday, 15 August 2008 - An Eastern Cooperative Oncology Group performance status (ECOG PS) of 2/3 can quantify cancer patients' well being and may be used to select patients for treatment. Shuch et al.(2008) investigated the...
Authors: Shuch et al.
Climate-related increase in the prevalence of urolithiasis in the United States
Thursday, 7 August 2008 - Brikowski et al. (2008) analyzed the effect of global warming on the prevalence of kidney stones in the United States.
An unanticipated result of global warming is the likely northward expansion of the...
Authors: Brikowski et al.
Laparoscopic port-site metastasis in urologic surgery
Tuesday, 5 August 2008 - Port-site metastasis has been an increasing concern with the spread of laparoscopy in managing urologic malignancies. Eng et al. (2008) reviewed port-site metastases reported in the urologic oncology...
Authors: Eng et al.
Effect of cryoablation on the histologic interpretation of intraoperative biopsy of small clear cell renal carcinoma and renal oncocytoma
Tuesday, 5 August 2008 - Chen et al. (2008) evaluated the effects of the first freeze-thaw cycle of cryoablation on Fuhrman grade, histology, and tumor architecture of small clear cell renal carcinomas and renal oncocytomas using...
Authors: Chen et al.
Loss of galectin-3 expression correlates with clear cell renal carcinoma progression and reduced survival
Saturday, 2 August 2008 - Galectin-3 is a member of the glycoprotein family, actively involved in various biological interactions including cell growth, cell adhesion, cell differentiation and apoptosis. Merseburger et al. (2008)...
Authors: Merseburger et al.
An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma
Wednesday, 30 July 2008 - Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy. A substantial proportion of patients are at risk for recurrence because no effective adjuvant therapy exists. Wood...
Authors: Wood et al.
Serotonin used as prognostic marker of urological tumors
Monday, 28 July 2008 - In regard to therapy and prognosis of urological tumors, specific tumor markers are lacking, especially in renal and urinary bladder carcinoma. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine...
Authors: Jungwirth et al.
Feasibility of laparoscopic partial nephrectomy after previous ipsilateral renal procedures
Sunday, 27 July 2008 - Previous renal surgery has been considered a relative contraindication to laparoscopic partial nephrectomy (LPN) because of perirenal surgical adhesions. Turna et al. (2008) reported their experience with...
Authors: Turna et al.
