key articles
Survival in Bladder and Renal Cell Cancers Is Familial
Sunday, 6 April 2008 - It is known that having family members with cancer associates with increased risk for bladder and renal cell cancers. However, this association with survival has not been examined. Ji et al. (2008) analysed...
Authors: Ji et al.
IMP3 expression - marker for prognosis of metastatic progression
Thursday, 3 April 2008 - High-quality external validation studies highlight the importance for proper translation of prognostic markers into the clinical setting. Hoffmann et al. (2008) examined associations of the insulin-like...
Authors: Hoffmann et al.
Poor prognosis for underweight patients with renal cell carcinoma after nephrectomy
Wednesday, 2 April 2008 - Obesity people have as high as twice the risk of developing renal cell carcinoma (RCC). However, patients with RCC and a higher body mass index (BMI) at diagnosis have better survival than those with a...
Author: Haferkamp et al.
The clinical significance of micro-metastatic lymph node disease in kidney and bladder cancer
Thursday, 27 March 2008 - MILAN - Treatment failure in bladder and kidney cancer following definitive surgery with curative intent is one of the most important urological problems unsolved so far. In his today's state-of-the-art...
By: Franz-Guenter Runkel
Debate on nephrectomy in EAU-ESMO joint session
Thursday, 27 March 2008 - A joint session of the European Association of Urology (EAU) and the European Society for Medical Oncology (ESMO) featuring a debate on metastatic renal cell carcinoma (mRCC) highlighted the...
By: Joel Vega
Laparoscopic partial nephrectomy for hilar tumors
Saturday, 22 March 2008 - Laparoscopic nephron-sparing surgery is an alternative to the open approach, offering reduced blood loss, operative time, and analgesia requirements and more rapid convalescence. Richstone et al. (2008)...
Authors: Richstone et al.
Statins and reduced risk of renal cell carcinoma
Thursday, 20 March 2008 - Statins (also known as 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are commonly used cholesterol-lowering agents and have shown inhibitory effect on prostate cancer and baldder cancer. In...
Authors: Khurana et al.
High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma
Friday, 14 March 2008 - The Ran small GTPase (Ran) is involved in the regulation of nuclear transport, microtubule nucleation and dynamics, and spindle assembly. To address the question of whether Ran protein is associated with...
Authors: Abe et al.
Von Hippel-Lindau tumor suppressor gene loss in renal cell carcinoma promotes oncogenic epidermal growth factor receptor signalling via Akt-1 and MEK1
Thursday, 13 March 2008 - Clear-cell renal cell carcinoma (RCC) is the most prevalent form of kidney cancer and is frequently associated with loss of von Hippel-Lindau (VHL) gene function, resulting in the aberrant...
Authors: Lee et al.
Analysis of clinicopathologic predictors of oncologic outcome provides insight into the natural history of surgically managed papillary renal cell carcinoma
Saturday, 8 March 2008 - To gain further insight into the natural history of papillary renal cell carcinoma (pRCC), Margulis et al. (2008) evaluated oncologic impact of important clinical and pathologic prognostic factors and...
Authors: Margulis et al.
