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Continuous or Six Months a Year Maximal Androgen Blockade for Prostate Cancer

Authors: Irani et al.

Friday, 16 May 2008 - Irani et al. (2008) evaluated interrupted androgen suppression (SIAS) 6 months a year compared with continuous androgen suppression (CAS) in prostate cancer treatment.

All patients underwent maximal androgen blockade for 6 mo. Then, depending on the randomisation arm, they continued (CAS) or...

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Association of Lower Plasma Adiponectin Levels with Clear-Cell Kidney Carcinoma

Friday, 16 May 2008 - Pinthus et al. (2008) examined a possible relationship between plasma adiponectin levels and renal cell carcinoma (RCC). Adiponectin, a cytokine secreted by adipocytes, is a potent antiangiogenic factor. Plasma levels of adiponectin in patients with RCC and tumor adiponectin receptors R1 and R2...

Authors: Pinthus et al.

Hormonal profile of diabetic men and the potential link to prostate cancer

Thursday, 15 May 2008 - Men with diabetes may be at reduced risk for prostate cancer as compared to men without diabetes. Kasper et al. (2008) investigated potential biological mechanisms, hormonal profiles of diabetic men, and compared with non-diabetic controls.

In the Health Professionals Follow-Up Study, plasma...

Authors: Kasper et al.

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Impact of Chronic PDE5 Inhibitors on Erectile Function of Diabetic Rats

Thursday, 15 May 2008 - Diabetic men generally have reduced efficacy with PDE-5 inhibitors (PDE5i) for the treatment of erectile dysfunction (ED). De Young et al. (2008) determined whether chronic vardenafil exposure alters cavernous protein expression predicting improved erectile function in diabetes.

Forty-two...

Prostate-specific antigen velocity and prostate cancer distant metastases

Thursday, 15 May 2008 - In men with prostate cancer, pretreatment prostate-specific antigen velocity (PSAV) is a predictor of biochemical and survival outcomes in patients undergoing radical prostatectomy (RP). The utility of pretreatment PSAV in predicting outcomes after radiotherapy (RT), with or without...

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Association of prostate cancer with body size in childhood and young adulthood

Thursday, 15 May 2008 - Body size relatively early in life may influence men's later rate of prostate cancer. Robinson et al. (2008) searched for published, English-language studies of the association between prostate cancer incidence or mortality and body size between ages 5 and 29 years.

The authors summarized...

Changes in muscle, fat and bone mass after androgen blockade for prostate cancer

Wednesday, 14 May 2008 - Galvao et al. (2008) assessed the effects of androgen deprivation therapy (ADT) on whole-body and regional muscle, fat and bone mass in men with prostate cancer without metastatic bone disease.

Seventy-two men aged 44-88 years underwent spine, hip and whole-body dual-energy X-ray...

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Radical prostatectomy versus radiation therapy in men with T3 prostate cancer

Tuesday, 13 May 2008 - At the 23rd EAU annual congress held in Milan, March 2008, Djavan et al. presented oncological outcomes of radical prostatectomy and radiation therapy in men with cT3 prostate cancer and to analyse independent factors allowing an accurate patient selection.

Between 1993 and 2006 a total of 695...

Case Discussions on Renal Cell Cancer: timing of treatment, Last Part

Friday, 9 May 2008 - At the 23rd Annual EAU Congress held in Milan, Italy, Prof. Axel Heidenreich (Cologne, Germany) chaired the case discussions on the timing of treatment for renal cancer and noted that nowadays there is a wide range of treatment options for managing the disease including active surveillance,...

Urology Week 2008: attention for urological conditions

Tuesday, 22 April 2008 - Every year 225,000 new cases of prostate cancer are detected in Europe alone. At least 1 in 10 people age 65 or older suffers from urinary incontinence, the involuntary loss of urine. And epidemiologic data indicate that erectile dysfunction (ED) is a significant problem among men worldwide....

3rd Masterclass on medical treatment for urological cancer

Tuesday, 15 April 2008 - The masterclass is a prime venue to scrutinise current practices and survey the latest therapies that are still being tried or tested in various medical disciplines involved in cancer therapy.There was a need to open the masterclass to other specialists, such as our colleagues from medical...