In diabetic men, ejaculatory dysfunction is as prominent as ED

Wednesday, 15 July 2009- Ejaculatory Dysfunction (EjD) is as important as ED (Erectile Dysfunction) in terms of overall sexual dysfunction in men with diabetes mellitus, with anejeculation being the most frequent of EjD disorders, was the conclusion of a report by a team of Japanese scientists.

The findings of the study were presented at the 3rd International Consultation on Sexual Medicine, which was held on 10-13 July 2009 in Paris.

Fifty-five patients presenting with EjD consequent to diabetes who visited Chubu-Rosai Hospital in Nagoya, Japan, from December 1983 to March 2008 were reviewed during the investigation. These subjects accounted for 8.4% of all EjD patients (657 patients).

The average age of patients was 46.14, but the overall age span was very wide, ranging from 27 to 77 years. Twenty-three patients had fathered children, whereas 32 subjects had not. Twenty-six patients hopedfor a child.

Forty-four patients (80%) displayed type 2 diabetes: blood glucose level, 69-486 mg/dl (average, 198mg/dl), HbA1C, 5.0-13.5% (average, 8.35%), DM contraction period, 0.5-33 years (average, 11.0 years). Treatment for their primary condition consisted of diet therapy (eight individuals), oral diabetes remedy (22) and insulin (23).

Twenty-one, twenty-five and nine patients demonstrated neuropathy (42%), retinopathy (50%) and nephropathy, respectively. Forty-nine patients (89%) reported anejaculation (emissionless or retrograde ejaculation), whereas sixpatients (11%) exhibited other forms of EjD (premature ejaculation, etc.).

Initial treatment for anejaculation included oral medications: yohimbine (14 cases; effectivein 1), amoxapine (9; effective in 3), imipramine (4; effective in 1) and ephedrine (7; effective in 2).

Electro-ejaculation was performed in five individuals; moreover, one pregnancy was achieved following artificial insemination with recovered semen. Penile vibratory stimulation was conducted in 15 subjects (effective in 3).

The authors concluded that anejaculation is the most frequent type of EjD associated with diabetes mellitus patients. They suggest that the first-line therapy should consist consists of oral medication. In instances in which medications are ineffectual or children are desired, electro-ejaculation or penile vibratory stimulation proved to yield some result.

Source: Otani T. et al. Clinical analysis of ejaculatory dysfunction in men with diabetes. 3rd International Consultation on Sexual Dysfunction, Poster session, Poster#3.

Edited by: ES


eXTReMe Tracker