Reoperation 10 years after surgically managed pelvic organ prolapse and urinary incontinence
Saturday, 17 May 2008 - Denman et al. (2008) measured the 10-year risk of reoperation for surgically treated pelvic organ prolapse and urinary incontinence (POPUI) in a community population.
The authors conducted a prospective cohort analysis of 374 women who were > 20 years old and who underwent surgery for POPUI...
Authors: Denman et al.
Diagnosis and treatment of female sexual dysfunction
Saturday, 17 May 2008 - In a recent paper, Frank et al. (2008) discussed diagnosis and treatment of female sexual dysfunction. Female sexual complaints are common, occurring in approximately 40 percent of women. Decreased desire is the most common complaint. Normal versus abnormal sexual functioning in women is poorly...
Authors: Frank et al.
Prostate-specific antigen and prostate cancer: prediction, detection and monitoring
Saturday, 17 May 2008 - In a review, Lilja et al. (2008) examined current evidence for the association between prostate-specific antigen (PSA) and prostate cancer risk, disease outcome and recurrence. The authors also described the use of PSA testing for long-term prediction of prostate cancer and the use of PSA...
Authors: Lilja et al.
Sex hormone-binding globulin to predict extraprostatic tumor extension of prostate cancer patients
Friday, 16 May 2008 - Lee et al. (Lee et al., 2008) investigated the relationships of serum sex hormone-binding globulin (SHBG) level with known prognostic factors for prostate cancer in men who received radical retropubic prostatectomy (RRP) for clinically localized prostate cancer.
Preoperative serum levels of SHBG...
Genomic DNA hypomethylation as a biomarker for bladder cancer
Friday, 16 May 2008 - DNA hypomethylation has been suggested to cause genomic instability and increase cancer risk. Moore et al. (2008) tested the hypothesis that DNA hypomethylation is associated with increased risk of bladder cancer.
The authors measured cytosine methylation (5-mC) content in genomic DNA from blood...
Authors: Moore et al.
Predicting the Probability of Deferred Radical Treatment for Localised Prostate Cancer
Friday, 16 May 2008 - Outcome data from a prospective study of active surveillance of localised prostate cancer were analysed by van As et al. (2008) to identify factors, present at the time of diagnosis, that predict subsequent radical treatment.
Eligible patients had clinical stage T1-T2a, N0-Nx, M0-Mx...
Authors: van As
Impact of Chronic PDE5 Inhibitors on Erectile Function of Diabetic Rats
Thursday, 15 May 2008 - Diabetic men generally have reduced efficacy with PDE-5 inhibitors (PDE5i) for the treatment of erectile dysfunction (ED). De Young et al. (2008) determined whether chronic vardenafil exposure alters cavernous protein expression predicting improved erectile function in diabetes.
Forty-two...
Authors: De Young et al.
Prostate-specific antigen velocity and prostate cancer distant metastases
Thursday, 15 May 2008 - In men with prostate cancer, pretreatment prostate-specific antigen velocity (PSAV) is a predictor of biochemical and survival outcomes in patients undergoing radical prostatectomy (RP). The utility of pretreatment PSAV in predicting outcomes after radiotherapy (RT), with or without...
Authors: Palma et al.
Cardiovascular risk in long-term survivors of testicular cancer
Thursday, 15 May 2008 - Long-term survivors of testicular cancer (TC) after cisplatin-based chemotherapy have an increased risk of cardiovascular disease. In a cross-sectional study, Vaughn et al.(2008) objectively assessed cardiovascular risk, subclinical atherosclerosis, and endothelial function in long-term...
Authors: Vaughn et al.
The prognostic role of the pathological T2 subclassification for prostate cancer
Wednesday, 14 May 2008 - Van Oort et al. (2008) evaluated the prognostic role of the 2002 Tumour-Nodes-Metastasis (TNM) pT2 subclassification for biochemical recurrence (BCR) after radical prostatectomy (RP) for prostate cancer.
The 1997 TNM staging system is based on one subdivision for organ-confined prostate...
Authors: van Oort
