Effect of smoking on the male excess of bladder cancer: A meta-analysis and geographical analyses
Thursday, 13 November 2008 - Smoking is considered the primary risk factor for bladder cancer. Although smoking prevalence and bladder cancer incidence vary around the world, bladder cancer is on average 4 times more common in males than in females. Hemelt et al. (2008) described the observed male-female incidence...
Authors: Hemelt et al.
Quality of Life assessment after Radical Prostatectomy or Watchful Waiting
Wednesday, 12 November 2008 - Quality-of-life outcomes are important in the choice of treatment strategy for men with localized prostate cancer. Johansson et al. (2008) evaluated how follow-up time, number of physical symptoms, and presence of androgen deprivation affected quality of life among men randomized to...
Authors: Johansson et al.
Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction and Lower Urinary Tract Symptoms
Wednesday, 12 November 2008 - The relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) and the potential interplay of phosphodiesterase type 5 inhibitors (PDE5-I) have clinical implications for both patient screening and treatment. Kohler and McVary (2008) described the current...
Authors: Kohler & McVary
PSA velocity predicts high-risk prostate cancer
Tuesday, 11 November 2008 - The identification of high-risk prostate cancer in men is improved by measuring prostate-specific antigen (PSA) velocity, but not PSA doubling time, US researchers have discovered.
PSA velocity is reportedly associated with life-threatening prostate cancer, but the relative ability of PSA...
Edited by: JV
Randomized Phase II Trial Evaluation of Erectile Function after Prostatectomy
Tuesday, 11 November 2008 - Nonrandomized studies of unilateral nerve-sparing (UNS) radical prostatectomy (RP) have reported improved recovery of erectile function if the sacrificed cavernous nerve is reconstructed with a sural nerve graft (SNG). Davis et al. (2008) determined whether UNS RP plus SNG results in a 50%...
Authors: Davis et al.
Metastatic renal cell carcinoma: population-based 25-year follow-up
Monday, 10 November 2008 - Renal cell carcinoma (RCC) is the 6th leading cause of death in developed countries. A third of all RCC patients are confronted with metastatic disease. Since their approval in 2005 and 2006 in the USA, new targeted therapies may lead to substantial progress. Schlesinger-Raab et al. (2008)...
Authors: Schlesinger-Raab et al.
Current criteria for active surveillance in low-risk prostate cancer patients
Monday, 10 November 2008 - Active surveillance (AS) represents a treatment option for select patients with low-risk, organ-confined prostate cancer (PCa). Suardi et al. (2008) addressed the rates of misclassification associated with the use of 5 different clinical criteria for AS. Misclassification was defined as the...
Authors: Suardi et al.
US study says finasteride not linked to increased hip fracture risk among men
Monday, 10 November 2008- A study published in the Journal of the American Medical Association (JAMA) reported that use of finasteride, a 5-alpha reductase inhibitor commonly used to treat benign prostatic hyperplasia (BPH), does not appear to be linked with an increased incidence of hip fractures in men. On the...
Edited by: JV
Gestational hypertension, preeclampsia and risk of testicular cancer
Friday, 7 November 2008 - Altered levels of pregnancy hormones have been suggested to initiate testicular cancer prenatally in the male fetus. The placenta is the main source of pregnancy hormones, and pregnancy hypertension and preeclampsia are associated with placental malfunction, including altered levels of...
Edited by: JV
Cholesterol-lowering drugs may lower PSA but impact on cancer risk remains unknown
Thursday, 6 November 2008 - Popular cholesterol-busting drugs such as statins appear to lower men's PSA values along with their cholesterol levels, but whether the drugs prevent prostate cancer growth remains unknown, according to researchers at the Duke Prostate Center and the Durham Veterans Affairs Medical Center...
Edited by: JV
