Prostate cancer gene PCA3 role in urological practice
Thursday, 9 October 2008- The diagnosis of prostate cancer (PCa) in everyday practice is currently done with digital rectal examination (DRE) and the widely used PSA which helps for early detection of prostate cancer. But PSA, which is not specific for prostate cancer, has increased the number of prostate...
Source: Ilievski, A. et al.
Concomitant percutaneous nephrolithotomy and transperitoneal laparoscopic pyeloplasty for ureteropelvic junction obstruction complicated by stones
Wednesday, 8 October 2008 - Agarwal, et al. investigated concomitant percutaneous nephrolithotomy and transperitoneal laparoscopic pyeloplasty for patients with ureteropelvic junction obstruction complicated by stones.
The authors said ureteropelvic junction (UPJ) obstruction and stones can co exist and noted...
Authors: Anshuman Agarwal, et al.
Prognostic significance of cancer volume involving seminal vesicles in patients with pT3bpN0 prostate cancer
Tuesday, 7 October 2008 - Yamamoto et al. (2008) studied the prognostic effect of the prostate cancer (PCa) volume involving the seminal vesicles (CVSVs) in the radical prostatectomy specimen from patients with Stage pT3bpN0 PCa.
The authors retrospectively reviewed the clinical records of 27 patients with Stage...
Authors: Yamamoto et al.
Contemporary inguinal lymph node dissection: minimizing complications
Monday, 6 October 2008 - In a review, Spiess et al. (2008) described the morbidity of inguinal lymph node dissection (ILND) performed as part of the management of penile cancer as well as recent modifications that may reduce the incidence of complications.
The authors reviewed the literature using Pubmed© for studies...
Authors: Spiess et al.
No effect of statins on biochemical outcomes after radiotherapy for localized prostate cancer
Monday, 6 October 2008 - Soto et al. (2008) examined the effect of concurrent statin use during definitive radiotherapy (RT) on the biochemical outcomes for localized prostate cancer.
A total of 968 patients treated with RT had information about medication use available. Of these, 23% had been taking using statins...
Authors: Soto et al.
Targeting the stromal androgen receptor in primary prostate tumors at earlier stages
Monday, 6 October 2008 - To differentiate roles of androgen receptor (AR) in prostate stromal and epithelial cells, Niu et al. (2008) have generated inducible-(ind)ARKO-TRAMP and prostate epithelial-specific ARKO TRAMP (pes-ARKO-TRAMP) mouse models, in which the AR was knocked down in both prostate epithelium and...
Authors: Niu et. al.
Testicular metastases: a poor prognostic factor in patients with advanced prostate cancer
Sunday, 5 October 2008 - Prostate cancer is the most frequently diagnosed neoplasm in men. In some patients, however, the disease pursues a clearly more aggressive course. Testicular metastases from prostate cancer are rare events that have been previously reported; however, its frequency and clinical meaning are not...
Authors: Korkes et al.
A review of high-risk prostate cancer and the role of neo-adjuvant and adjuvant therapies
Sunday, 5 October 2008 - High-risk, localized prostate cancer represents a complex and diverse disease with many available treatment modalities. Patients are often deemed high risk because they are at increased risk for biochemical failure after primary intervention. However, these "high-risk" men may not be...
Authors: Gonzalez et al.
Repeating an abnormal prostate-specific antigen level
Sunday, 5 October 2008 - To examine the practice of repeating an abnormal prostate-specific antigen (PSA) level before proceeding to prostate biopsy, Connolly et al. (2008) assessed the pattern of PSA change following an initially raised (> /=4.0 ng ml(-1)) PSA, and the relationship of this to prostate cancer...
Authors: Connolly et al.
Association of "fibroblast growth factor receptor 4" genetic polymorphisms with prostate cancer risk and prognosis
Saturday, 4 October 2008 - The fibroblast growth factor receptor 4 (FGFR4, a human gene) is thought to be involved in many critical cellular processes and has been associated with prostate cancer risk. Four single nucleotide polymorphisms (SNPs) within or near FGFR4 were analyzed in a population-based study...
Authors: Fitzgerald et al.
