Association of "fibroblast growth factor receptor 4" genetic polymorphisms with prostate cancer risk and prognosis
Saturday, 4 October 2008 - The fibroblast growth factor receptor 4 (FGFR4, a human gene) is thought to be involved in many critical cellular processes and has been associated with prostate cancer risk. Four single nucleotide polymorphisms (SNPs) within or near FGFR4 were analyzed in a population-based study...
Authors: Fitzgerald et al.
Biopsy tissue microarray study of Ki-67 expression in untreated, localized prostate cancer managed by active surveillance
Saturday, 4 October 2008 - Active surveillance provides a unique opportunity to study biomarkers of prostate cancer behaviour, although only small volumes of tumor tissue are typically available. Jhavar et al. (2008) evaluated a technique for constructing tissue microarrays (TMAs) from needle biopsies for assessing...
Authors: Jhavar et al.
Obesity is a significant risk factor for prostate cancer at the time of biopsy
Saturday, 4 October 2008 - Studies suggest obesity is associated with decreased prostate cancer risk. Freedland et al. (2008) hypothesized that obesity is biologically associated with increased risk, although this is obscured owing to hemodilution of prostate-specific antigen (PSA) and larger prostate size.
The...
Authors: Freedland et al.
Clean intermittent catheterization in children through a continent catheterizable channel
Friday, 3 October 2008 - Sultan et al. (2008) evaluated the role of clean intermittent self-catheterization through a continent catheterizable Mitrofanoff channel in an augmented bladder in children with bladder dysfunction and outlet obstruction.
The authors retrospectively analyzed the records of 82 patients...
Authors: Sultan et al.
Patient reported and anatomical outcomes after surgery for pelvic organ prolapse
Friday, 3 October 2008 - El-Azab et al. (2008) modified Pelvic Floor Distress Inventory (PFDI) and Pelvic Floor Impact Questionnaire (PFIQ) to assess pelvic organ prolapse (POP) in Arabic Muslim women. They also compared functional and anatomical outcomes of POP repair.
A characteristic (prayer) was added to PFIQ....
Authors: El-Azab et al.
Transcorporal artificial urinary sphincter placement for incontinence in high-risk patients after treatment of prostate cancer
Friday, 3 October 2008 - Aaronson et al. (2008) investigated the transcorporal (TC) vs standard (ST) approach of artificial urinary sphincter (AUS) placement for incontinence after treatment of prostate adenocarcinoma (PCa) with radiotherapy or surgery, or both.
A database was created to include the data from all...
Authors: Aaronson et al.
Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: A dose finding study
Friday, 3 October 2008 - Phosphodiesterase type 5 inhibitors are widely used to treat erectile dysfunction. Preliminary data have suggested phosphodiesterase type 5 inhibitor efficacy in men with lower urinary tract symptoms (LUTS) associated with clinical benign prostatic hyperplasia (BPH). Roehrborn et al. (2008)...
Authors: Roehrborn et al.
Extracorporeal shock wave lithotripsy in pediatric patients by using a late generation portable lithotripter
Friday, 3 October 2008 - Kidney stones in children are increasing in incidence. The continued evolution of stone treatment modalities, including shock wave lithotripsy, makes the assessment of continuous outcomes essential. Nelson et al. (2008) described contemporary shock wave lithotripsy outcomes in pediatric...
Authors: Nelson et al.
Long-term followup of dermal grafts for repair of severe penile curvature
Thursday, 2 October 2008 - There is some reluctance to use dermal grafts for augmenting the tunica albuginea to correct severe forms of chordee (a condition in which the head of the penis curves downward or upward, at the junction of the head and shaft of the penis). The main concern is that by violating the integrity...
Authors: Badawy & Morsi
Is low bladder compliance predictive of detrusor overactivity?
Thursday, 2 October 2008 - Bladder compliance (BC) expresses the relationship between bladder volume and bladder pressure and is generally regarded as a measure of bladder stiffness or distensibility. Many types of voiding dysfunction have been associated with low BC such as detrusor overactivity (DO). It has...
Authors: Harding et al.
